Allen Zweben

Associate Dean of Academic Affairs and Research

Bio:

Dr. Zweben received his doctorate in social welfare from Columbia University in New York in 1977.  From 1975 until 1986 he had a cross appointment at the Addiction Research Foundation and the University of Toronto, Canada where he was Director of Psychosocial Research and Associate Professor, respectively.  Dr. Zweben was at the University of Wisconsin, Milwaukee, from 1986-2004 where he was Director of the Center for Addiction and Behavioral Health Research (CABHR) and Professor.  In 2005, Dr. Zweben returned to Columbia University where he is currently Professor and Associate Dean for Research and Sponsored Projects in the School of Social Work.  

Dr. Zweben is an expert in areas related to addiction medicine, including screening and assessment, brief intervention, motivational interviewing, cognitive-behavioral therapy, twelve-step facilitation therapy, HIV-risk reduction strategies, couples and family treatment, study recruitment/ compliance techniques, patient-treatment matching, medications development, and outcome measurement.  His research and publications have focused primarily on innovative assessment and treatment approaches for substance use problems. 

Dr. Zweben has been a  principal investigator of numerous behavioral and medication trials including Project MATCH, an NIAAA-funded, landmark, patient-treatment matching study, the COMBINE study, a NIAAA-funded project examining the efficacy of combining pharmacotherapy and psychotherapy interventions for alcohol problems and HEART-to-HEART, a NIAAA-funded study testing the efficacy of combining alcohol and HIV risk reduction interventions for women at risk for HIV infection who are seeking help for alcohol problems. Currently, Dr. Zweben is testing a new alcohol medication combined with medical management in treating individuals with alcohol problems.

Research Interests:

  • Screening and assessment
  • Brief intervention
  • Motivational interviewing
  • Cognitive-behavioral therapy
  • Twelve-step facilitation therapy
  • HIV-risk reduction strategies
  • Couples and family treatment,
  • Study recruitment/compliance techniques
  • Patient-treatment matching
  • Medications development
  • Outcome measurement

Awards:

  • Proclamation from the Mayor, City of Milwaukee, for distinguished contributions to research and public services
  • Appreciation from the Board of Regents, University of Wisconsin Systems, for dedicated services, scholarship and many distinguished contributions to the University of Wisconsin-Milwaukee.
  • Commendation from the Office of the Governor in the State of Wisconsin in recognition of leadership in advancing alcohol and behavioral health sciences

Current Projects:

  • Phase 2 Study of LY2196044 Compared with Placebo in the Treatment of Alcohol Dependence
  • Indefinite Delivery Indefinite Quantity (IDIQ) project, research and evaluation of services delivered on substance use and mental health issues
  • Combined Treatment of Alcohol Dependent Women with PTSD
  • HIV & Alcohol Risk Reduction for Women (Heart to Heart for Women)
  • Combining Brief and Pharmacotherapies for Alcohol Problems

Selected Publications & Presentations:

Books

Forcehimes, A., Miller, W. R., & Zweben, A. (in process). Substance abuse treatment. New York: Guilford Press.

Book Chapters

Rose, S., & Zweben, A. (2003).  Interrelationship of substance abuse and social problems. In W. R. Miller & C. Weisner (Eds.), Addressing addictions through health and social systems (pp. 145-156). New York: Plenum Press.

Steinberg, K., Babor, T., Zweben, A., Cisler, R., Stout, R., Anton, R., Allen, J., & Tonigan J. S., (2003). Treatment effects across multiple dimensions of outcome. In T. F. Babor & F. K. Del Boca (Eds.), Treatment matching in alcoholism (pp. 150-165). Cambridge: Cambridge University Press.

Zweben, A., Del Boca, F. K., Mattson, M. E., & McRee, B. (2003). Client characteristics and implementation of the research protocol.  In T. F. Babor & F. K. Del Boca (Eds.), Treatment matching in alcoholism (pp. 62-80). Cambridge: Cambridge University Press.

Zweben, A., Rose, S., & Stout, R. (2003). Case monitoring and motivational style brief intervention. In R. K. Hester & W. R. Miller (Eds.), Handbook of alcoholism treatment approaches: Effective alternatives (3rd ed.) (pp. 113-130). New York: Allyn & Bacon.

Burke, B., Vassilev, G., Kantchelov, A., & Zweben, A. (2002).  Motivational interviewing with couples/significant others.  In W. R. Miller & S. Rollnick (Eds.), Motivational interviewing (2nd ed.) (pp. 347-361). New York: Guilford Press.

Zweben, A. (2002). Diagnosis and assessment of alcohol use disorders. Module developed for social work education curriculum for the prevention and treatment of alcohol problems, NIAAA Curriculum Task Force.

Zweben, A. (2002). Motivation and treatment interventions. Module developed for social work education curriculum for the prevention and treatment of alcohol problems, NIAAA Curriculum Task Force.   

Zweben, A., & Zuckoff, A. (2002). Treatment preparation, induction and adherence. In W. R. Miller & S. Rollnick (Eds.), Motivational interviewing (2nd ed.) (pp. 299-319). New York: Guilford Press.

Journal Articles

Zweben, A., Fucito, L. M., & O’Malley, S. S. (in press). Effective strategies for maintaining research participation in clinical trials. Drug Information Journal.

Zweben, A. (in press). Introduction. In Medication maintenance for alcohol problems, Treatment Improvement Protocol (TIPS), Center for Substance Abuse Treatment, SAMSHA. 

LoCastro, J., Youngblood, M. A., Cisler, R., Mattson, M. M.,  Zweben, A., & Anton, R. (2009). Alcohol treatment effects on secondary non-drinking outcomes and quality of life: The COMBINE Study. Journal of Studies on Drugs and Alcohol, 70(2), 186-196

Zweben, A., Pettinati, H., Weiss, R., Youngblood, M., Cox, C., Mattson, M., Gorroochurn, P., & Ciraulo, D. (2008). Relationship between patient adherence and treatment outcomes: The COMBINE Study. Alcoholism: Clinical and Experimental Research, 32(9), 1661-1669; adapted for publication in the Brown University Digest of Addiction of Theory and Application, 27(12), 1, 6-7.

Anton, R. F., O’Malley, S. S., Ciraulo, D. A., Cisler, R. A., Couper, D., Donovan, D. M., Gastfriend, D. R., Hosking, J. D., Johnson, B. A., LoCastro, J. S., Longabaugh, R., Mason, B. J., Mattson, M. E., Miller, W. R., Pettinati, H. M., Randall, C. L., Swift, R., Weiss, R., Williams, L. D., & Zweben, A. for the COMBINE Research Group, (2006).  Effect of combined pharmacotherapies and behavioral intervention (COMBINE Study) for alcohol dependence.  Journal of the American Medical Association, 295(17), 2003-2017.

Zweben, A. (2006).  Screening and brief intervention In W. R. Miller, C. Baca, W. M. Compton, D. Ernst, J. K. Manuel, B. Pringle, C. R. Schermer, R. D. Weiss, M. L. Willenbring, & A. Zweben. Proceedings of a roundtable addressing substance abuse in health care settings. Alcoholism: Clinical and Experimental Research, 30, 292-302.

Cisler, R. A., Kowalchuk, R. Saunders, S., Zweben A., & Trinh, H. Q. (2005). Clinical significance of Project MATCH: Methodological considerations in determining individual-level functional outcomes in alcoholism treatment research. Alcoholism: Clinical and Experimental Research, 29, 1991-2000. 

Kalichman, S. C., Weinhardt, L., Benotsch, E., Presser, K., Zweben, A., Bjodstrup, B., & Swain, G. (2005). Experimental components analysis of brief theory-based HIV/AIDS risk reduction counseling for sexually transmitted infection patients. Health Psychology, 24, 198-208.

Pettinati, H., Zweben, A., & Mattson, M. (Eds.). (2005). The COMBINE Study: Conceptual, methodological and practical issues in conducting a clinical trial that combines pharmacological and behavioral treatments. Journal of Studies on Alcohol, Supplement, 15.

Zweben, A., Barrett, D., Berger, L., & Tobin Murray, K. (2005). Recruiting and retaining participants in a combined behavioral and pharmacological clinical trial. Journal of Studies on Alcohol Supplement, 15, 72-81.

Weiss, R., LoCastro, J., Longabaugh, R., Miller, W. R., Swift, R., & Zweben, A. (2005). The use of psychotherapy with “no pills” treatment condition as part of a combined pharmacotherapy-psychotherapy research study of alcohol dependence.  Journal of Studies on Alcohol, Supplement, 15, 43-49. 

Donovan, D., Cisler, R., Longabaugh, R., Mattson, M., & Zweben, A. (2005). Quality of life as an outcome measure in clinical trials of medications to treat alcohol disorders. Journal of Studies on Alcohol Supplement, 15, 199-139.

Miller, W. R., LoCastro, J., Longabaugh, R., O’Malley, S., & Zweben, A. (2005). When worlds collide: Blending the diverse traditions of pharmacotherapy and psychotherapy research. Journal of Studies on Alcohol Supplement, 15, 17-23.

Longabaugh, R., Zweben, A., LoCastro, J., & Miller, W. R. (2005). Origins, issues and options in the development of the combined behavioral intervention. Journal of Studies on Alcohol Supplement, 15, 179-187. 

Zweben, A. (2005).  Frontiers of social work practice: Combined pharmacological and psychosocial interventions for substance use problems. Issues of Substance, National Association of Social Workers (Special Issue), 1, 11.

Zweben, A. (Ed.). (2005). Transdisciplinary social work research. Issues of Substance, National Association of Social Workers (Special Issue).

Anton, R., Pettinati, H., Zweben, A., Kranzler, H., Johnson, B., Bohn, M., McCaul, M. E., Anthenelli, R., Salloum, I., Galloway, G., Garbutt, J., Swift, R., Gastfriend, D., Kallio, A., & Karhuvaara, S. (2004). A multisite dose ranging study of nalmefene in the treatment of alcohol dependence. Journal of Clinical Psychopharmacology, 24(4), 421-428.

Zweben, A., & Cisler, R. (2003). Clinical and methodological utility of a composite outcome measure in alcohol treatment research. Alcoholism: Clinical and Experimental Research, 27(10), 1680-1685.

COMBINE Study Group (A. Zweben, Principal Investigator, UW-Milwaukee Clinical Research Unit) (2003). Testing combined pharmacotherapies and behavioral interventions in alcohol dependence (The COMBINE Study): Rationale and methods. Alcoholism: Clinical and Experimental Research., 27(7), 1107-1122.

COMBINE Study Group (A. Zweben, Principal Investigator, UW-Milwaukee Clinical Research Unit) (2003). Testing combined pharmacotherapies and behavioral interventions in alcohol dependence (The COMBINE Study): A pilot feasibility study.  Alcoholism: Clinical and Experimental Research, 27(7), 1123-1131. 

Cisler, R. A., Barrett, D., Zweben, A., & Berger, L. (2003). Integrating a brief motivational treatment for problem drinkers in a private outpatient clinic: Client characteristics, utilization of services and preliminary outcomes.  Alcoholism Treatment Quarterly, 21(3), 1-21. 

Kalichman, S. C., Cain, D., Zweben, A., & Swain, G. (2003). Sensation seeking, alcohol use and sexual risk behaviors among men receiving services at a clinic for sexually transmitted infections. Journal of Studies on Alcohol, 64(4), 564-569.

Presentations

Zweben, A. (2008, June). Two decades of treating addictive behaviors: integrating practice wisdom and evidence-based practice. Keynote Speaker. Presented at The 40th Anniversary Addictions Institute, NASW, New York City. 

Zweben, A. (2008, February). Combining pharmacotherapy and behavioral treatment for alcohol problems: The COMBINE study. Keynote Address. Presented at the Texas Research Society on Alcoholism 18th Annual Scientific Meeting, Austin, TX.

Zweben, A. (2008, January). Strategies for incorporating research and evaluation into social work practice: A critical appraisal. Keynote Address. Presented at the University of Toronto, Toronto, Ontario, Canada.

Zweben, A. (2008, January). Relationship between patient adherence and treatment outcomes. Society for Social Work Research, Annual Conference.